The aircraft was performing a cargo flight from Hong Kong to Istanbul with a refueling stop scheduled in Bishkek on behalf of Turkish Airlines, carrying a load of various goods for a total weight of 85,618 kilos. The approach to Bishkek-Manas Airport was completed in poor weather conditions with a vertical visibility estimated at 100 meters, a horizontal visibility about 150 meters and a runway visual range of 550 meters for runway 26. Apparently, the aircraft overshoot the runway and eventually crashed onto several houses located 1,000 meters past the runway 26 end (1,000 meters from runway 08 threshold). The aircraft was destroyed by impact forces and a post crash fire and all four crew members were killed. About 45 houses were damaged or destroyed and at least 28 people (among them six children) on the ground were killed. Its is reported that ten others were injured.