Crew was performing a cargo flight (AJK111) from Lagos to Accra on behalf of the DHL Group. Approach was completed in marginal weather conditions by night and heavy rain falls. After landing on runway 21, aircraft overrun, went trough a fence and crossed the Giffard Avenue on which it hit a minivan, a taxi and cyclist before coming to rest. As all four crew were unhurt, 12 people on the ground were killed (10 in the minivan, the passenger of a taxi and the cyclist). Aircraft was damaged beyond repair as all gear collapsed, both wings were damaged by impact forces and the tail partially separated. At the time of the accident, weather conditions were as follow: visibility 5 km, thunderstorm's activity with rain, broken clouds at 1'000 feet and few CB's above the terrain at 3'000 feet. It seems that aircraft landed long and the touch down was about half down the wet runway, reducing the landing distance available. Also, the friction coefficient was low.